Endoscopic Ultrasound

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 9  |  Issue : 6  |  Page : 385--391

Macroscopic on-site evaluation of biopsy specimens for accurate pathological diagnosis during EUS-guided fine needle biopsy using 22-G Franseen needle


Junichi Kaneko1, Hirotoshi Ishiwatari1, Keiko Sasaki2, Tatsunori Satoh1, Junya Sato1, Hiroyuki Matsubayashi3, Yohei Yabuuchi1, Yoshihiro Kishida1, Masao Yoshida1, Sayo Ito1, Noboru Kawata1, Kenichiro Imai1, Naomi Kakushima1, Kohei Takizawa1, Kinichi Hotta1, Hiroyuki Ono1 
1 Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan
2 Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan
3 Division of Endoscopy; Division of Genetic Medicine Promotion, Shizuoka Cancer Center, Shizuoka, Japan

Correspondence Address:
Dr. Hirotoshi Ishiwatari
Division of Endoscopy, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka
Japan

Background and Objectives: Measuring a visible core length during macroscopic on-site evaluation (MOSE) can be useful for accurate diagnoses during an EUS-guided fine needle biopsy (EUS-FNB). We aimed to estimate visible core cutoff lengths predictive of a correct diagnosis when using 22-gauge Franseen needles for biopsies from pancreatic masses. Materials and Methods: We assessed 77 consecutive patients who underwent EUS-FNB using 22-gauge Franseen needles for pancreatic masses between March 2018 and October 2018. At least two needle passes were performed in all patients, irrespective of the findings on MOSE. The endoscopists measured the visible cores using a ruler during MOSE. The first two passes were analyzed on a per pass basis, and the correlation between visible core lengths and diagnostic accuracy was evaluated. Results: We evaluated 150 needle passes of 75 patients. The accuracy per pass was 92% (138/150). The median length of the visible cores was 15 (range: 0–60) mm and they were significantly longer in the correct diagnosis group than in the incorrect diagnosis group. The accuracy correlated positively with the visible core length. Receiver-operating characteristic curve analysis of the visible core length for accuracy demonstrated an optimal cutoff value of 10 mm. On multivariate logistic regression, visible core lengths >10 mm independently affected the correct diagnosis (odds ratio: 5.1, P= 0.02). Conclusions: Visible cores exceeding 10 mm may be useful for correct diagnosis while using a 22-gauge Franseen needle for EUS-FNB from pancreatic masses.


How to cite this article:
Kaneko J, Ishiwatari H, Sasaki K, Satoh T, Sato J, Matsubayashi H, Yabuuchi Y, Kishida Y, Yoshida M, Ito S, Kawata N, Imai K, Kakushima N, Takizawa K, Hotta K, Ono H. Macroscopic on-site evaluation of biopsy specimens for accurate pathological diagnosis during EUS-guided fine needle biopsy using 22-G Franseen needle.Endosc Ultrasound 2020;9:385-391


How to cite this URL:
Kaneko J, Ishiwatari H, Sasaki K, Satoh T, Sato J, Matsubayashi H, Yabuuchi Y, Kishida Y, Yoshida M, Ito S, Kawata N, Imai K, Kakushima N, Takizawa K, Hotta K, Ono H. Macroscopic on-site evaluation of biopsy specimens for accurate pathological diagnosis during EUS-guided fine needle biopsy using 22-G Franseen needle. Endosc Ultrasound [serial online] 2020 [cited 2021 Jan 24 ];9:385-391
Available from: http://www.eusjournal.com/article.asp?issn=2303-9027;year=2020;volume=9;issue=6;spage=385;epage=391;aulast=Kaneko;type=0