Endoscopic Ultrasound

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 10  |  Issue : 6  |  Page : 424--430

Efficacy of the Franseen needle for diagnosing gastrointestinal submucosal lesions including small tumors


Kazumasa Nagai1, Atsushi Sofuni1, Takayoshi Tsuchiya1, Shin Kono1, Kentaro Ishii1, Reina Tanaka1, Ryosuke Tonozuka1, Shuntaro Mukai1, Kenjiro Yamamoto1, Yukitoshi Matsunami1, Yasutsugu Asai1, Takashi Kurosawa1, Hiroyuki Kojima1, Hiroshi Yamaguchi2, Toshitaka Nagao2, Takao Itoi1 
1 Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
2 Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan

Correspondence Address:
Takao Itoi
Department of Gastroenterology and Hematology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023
Japan

Background and Objectives: Several studies have demonstrated that EUS-guided fine-needle biopsy (EUS-FNB) is useful for diagnosing gastrointestinal subepithelial lesions (GI SELs). However, there is limited evidence regarding the use of Franseen needles during EUS-FNB for patients with GI SELs. In addition, the optimal approach for diagnosing small SELs is unclear. This study aimed to evaluate whether EUS-FNB using a Franseen needle was effective for diagnosing GI SELs, including small lesions. Methods: Between January 2013 and January 2020, 150 consecutive patients with GI SELs underwent EUS-FNA/FNB to achieve a histological diagnosis. Eighty-six consecutive patients who underwent EUS-FNB using a Franseen needle were compared to 64 patients who underwent EUS-FNA using a conventional needle. Results: The diagnostic yield was significantly higher using a Franseen needle than using a conventional needle (85% vs. 75%, P = 0.006). Furthermore, in cases with SELs that were <20 mm, the diagnostic yield was significantly higher using a Franseen needle than using a conventional needle (81% vs. 45%; P = 0.003). Multivariate analysis revealed that obtaining a sufficient diagnostic sample was independently predicted by Franseen needle use (adjusted odds ratio: 2.8, 95% confidence interval: 1.2–6.3; P = 0.01) and tumor size of >20 mm (adjusted odds ratio: 3.4, 95% confidence interval: 1.4–8.2; P = 0.006). Conclusion: Even when attempting to diagnose small GI SELs, EUS-FNB using a Franseen needle appears to provide a more efficient acquisition of true histological core tissue than using a conventional needle.


How to cite this article:
Nagai K, Sofuni A, Tsuchiya T, Kono S, Ishii K, Tanaka R, Tonozuka R, Mukai S, Yamamoto K, Matsunami Y, Asai Y, Kurosawa T, Kojima H, Yamaguchi H, Nagao T, Itoi T. Efficacy of the Franseen needle for diagnosing gastrointestinal submucosal lesions including small tumors.Endosc Ultrasound 2021;10:424-430


How to cite this URL:
Nagai K, Sofuni A, Tsuchiya T, Kono S, Ishii K, Tanaka R, Tonozuka R, Mukai S, Yamamoto K, Matsunami Y, Asai Y, Kurosawa T, Kojima H, Yamaguchi H, Nagao T, Itoi T. Efficacy of the Franseen needle for diagnosing gastrointestinal submucosal lesions including small tumors. Endosc Ultrasound [serial online] 2021 [cited 2022 Jan 27 ];10:424-430
Available from: http://www.eusjournal.com/article.asp?issn=2303-9027;year=2021;volume=10;issue=6;spage=424;epage=430;aulast=Nagai;type=0